Fueling Discovery

Gene By Gene

Deliver answers more effectively by using alternative, non-mammalian model organisms in early biological
and biomedical research.

Who We Are

About InVivo Biosystems

InVivo Biosystems provides essential services to help pharmaceutical,
nutracecal, biotechnology companies and academic research institutions around the globe accelerate their research and drug development efforts.

An expert in CRISPR genome editing, InVivo Biosystems creates custom genome edited C. elegans and zebrafish models to enable aging, and disease studies. InVivo Biosystems also develops and manufactures genotyping and phenotyping products, including instruments, reagents and consumables to allow researchers to explore and discover new phenotypes.

Our Service

What We Do

The InVivo Biosystems Technology provides the deep insights you need to make a go/no-go decision. Our data analysis and focused team of experts will also help you to understand the results and identify alternate routes and hypotheses you may not have seen previously.

CRISPR Genome Editing

InVivo Biosystems is a licensed CRISPR/Cas9 gene editing solutions provider.

Lifespan + Healthspan​

We offer a streamlined Longevity Platform to determine whether a compound can extend lifespan.

Toxicity Testing​

Toxicity studies using mammalian models are expensive and time- consuming1, 2.

Analytical Services​

Our early in-vivo analytical testing uses relevant and time-efficient whole animal models to help you shorten your project timeline.

How We Help

What Would You Like To Do?

Modify

Genome-edited C. elegans or zebrafish built to your specification.

Prepare

Start critical first steps in your experiment with worm-prep reagents & tools.

Measure

Visualize, measure C. elegans behavior and collect phenotypic output.

Our Guides

Point Mutation Publications

Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro-Muscular Function

Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG

Regulation of the sperm- to-oocyte transition in Caenorhabditis briggsaehermaphrodites by the Cbr-met-2 and Cbr-fem-3 genes

Let’s Connect With Us

Ready to connect with us to learn more about working with our company or our technology?

Flow Chart

The InVivo Biosystems Workflow

InVivo Biosystems provides a streamlined process for zebrafish gene editing services.

Project Design

Selection of best guide RNAs surrounding the locus to be edited.

01

sgRNA Testing

In vivo cutting assayed by PCR/ sequencing to determine the most efficient sgRNA.

02

Donor Homology Design

Repair templates are designed around high quality sgRNAs.

03

Germline Verification

Verification of germline editing

06

Clutch Verification

Evaluation of edit by PCR and/or sequencing of 10% of injected embryos.

05

Injection

Skilled injectors for rigorous in vivo testing of editing reagents.

04

Our Products

The Zebrafish Embryonic Genotyper (ZEG)

Rapid Automated DNA Extraction for Live Zebrafish Embryos

Comparison

Comparison of Zebrafish Genome Editing Methods

Offers Details

Injection Mix and sgRNA Validation Offerings

Standard Injection Mix

Standard Injection Mix + Screening Primers

Validated sgRNA Injection Mix

Complete Validated Injection Mix

Design

Injection Mix

Screening Reagents

In vivo sgRNA Testing

In vivo Editing Assesment

Pricing*

$995

$1,995

$3,995

$5,995

Timeline

4 weeks

6 weeks

8-10 weeks

12+ weeks

Complete Validated Injection Mix

Choose this option if you want a CRISPR knockin with completely validated reagents to use in your lab and to find your gene edited line. This is the best Custom Injection Mix option for the novice zebrafish line builder.

OUR VALIDATED sgRNA INJECTION MIX PLUS:

Full in vivo evaluation of somatic editing efficiency.

Confirmation of integration capacity of your edit into the zebrafish genome

Countaing The Stats

key Features

Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro-Muscular Function Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro-Muscular Function

1,325,317

over 1 million emails were sent

10,000

zebrafish were
reared

327

inquiries about New projects

107,045

100,000 zebrafish embroys were injected & 7,045 worms were injected

65,410

unique visits to our website

FAQs

Frequently Asked Question

Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.

Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.

Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.

Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.

Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.

Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.

Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.

Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.

Resourses

Latest Blog & News

Start A Project

Interested In StartingYour Zebrafish
Knock-In Tagging Project?

InVivo Biosystems provides a streamlined process for zebrafish gene editing services.

Submit your inquiry below & we will get back to you soon.

Partners

Our Clients

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An expert in CRISPR genome editing, InVivo Biosystems creates custom genome-edited C. elegans and zebrafish models to enable aging, developmental and disease studies. Our unique living platforms and technologies bridge the gap between cells and mice, providing faster.

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Contact Us

Headquarters: 1505 Westec Drive, Eugene, OR 97402

1.844.663.8749.

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