
Seventeen Minutes of Science: The Establishment and Growth of
Zebrafish as a Model System.
Tune in weekly to our virtual series “Seventeen Minutes of Science” every Tuesday at 11am PST / 2pm ET where we go live on …
Deliver answers more effectively by using alternative, non-mammalian model organisms in early biological
and biomedical research.
InVivo Biosystems provides essential services to help pharmaceutical,
nutracecal, biotechnology companies and academic research institutions around the globe accelerate their research and drug development efforts.
An expert in CRISPR genome editing, InVivo Biosystems creates custom genome edited C. elegans and zebrafish models to enable aging, and disease studies. InVivo Biosystems also develops and manufactures genotyping and phenotyping products, including instruments, reagents and consumables to allow researchers to explore and discover new phenotypes.
The InVivo Biosystems Technology provides the deep insights you need to make a go/no-go decision. Our data analysis and focused team of experts will also help you to understand the results and identify alternate routes and hypotheses you may not have seen previously.
InVivo Biosystems is a licensed CRISPR/Cas9 gene editing solutions provider.
We offer a streamlined Longevity Platform to determine whether a compound can extend lifespan.
Toxicity studies using mammalian models are expensive and time- consuming1, 2.
Our early in-vivo analytical testing uses relevant and time-efficient whole animal models to help you shorten your project timeline.
Genome-edited C. elegans or zebrafish built to your specification.
Start critical first steps in your experiment with worm-prep reagents & tools.
Visualize, measure C. elegans behavior and collect phenotypic output.
Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro-Muscular Function
Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG
Regulation of the sperm- to-oocyte transition in Caenorhabditis briggsaehermaphrodites by the Cbr-met-2 and Cbr-fem-3 genes
Selection of best guide RNAs surrounding the locus to be edited.
In vivo cutting assayed by PCR/ sequencing to determine the most efficient sgRNA.
Repair templates are designed around high quality sgRNAs.
Verification of germline editing
Evaluation of edit by PCR and/or sequencing of 10% of injected embryos.
Skilled injectors for rigorous in vivo testing of editing reagents.
Most commonly used in zebrafish labs to make fast and rapid genome edits
by random insertion of reporter cassettes (e.g. GFP, overexpression of mutant proteins). However, this method is not locus specific. It does not always recapitulate native expression patterns of gene and does not produce disruption in WT sequence.
InVivo Biosystems does not used the Tol2 method to produce mutants.
Most commonly used in zebrafish labs to make fast and rapid genome edits
by random insertion of reporter cassettes (e.g. GFP, overexpression of mutant proteins). However, this method is not locus specific. It does not always recapitulate native expression patterns of gene and does not produce disruption in WT sequence.
InVivo Biosystems does not used the Tol2 method to produce mutants.
Most commonly used in zebrafish labs to make fast and rapid genome edits
by random insertion of reporter cassettes (e.g. GFP, overexpression of mutant proteins). However, this method is not locus specific. It does not always recapitulate native expression patterns of gene and does not produce disruption in WT sequence.
InVivo Biosystems does not used the Tol2 method to produce mutants.
Choose this option if you want a CRISPR knockin with completely validated reagents to use in your lab and to find your gene edited line. This is the best Custom Injection Mix option for the novice zebrafish line builder.
Full in vivo evaluation of somatic editing efficiency.
Confirmation of integration capacity of your edit into the zebrafish genome
Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro-Muscular Function Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro-Muscular Function
over 1 million emails were sent
zebrafish were reared
inquiries about New projects
100,000 zebrafish embroys were injected & 7,045 worms were injected
unique visits to our website
Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.
Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.
Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.
Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.
Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.
Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.
Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.
Dr. Schrader begins by making incisions within the nasal passages
to access the internal bones and cartilage that support the nose.
Depending on the desired result, Dr. Schrader may remove some
bone and cartilage or add tissue from another area of the body or
with a synthetic filler.
Tune in weekly to our virtual series “Seventeen Minutes of Science” every Tuesday at 11am PST / 2pm ET where we go live on …
Tune in weekly to our virtual series “Seventeen Minutes of Science” every Tuesday at 11am PST / 2pm ET where we go live on …
Tune in weekly to our virtual series “Seventeen Minutes of Science” every Tuesday at 11am PST / 2pm ET where we go live on …
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